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Was ist menschliches Wachstumshormon (HGH)?



Menschliches Wachstumshormon (Somatotropin) ist ein Peptidhormon, das in der Hirnanhangdrüse produziert wird. Es steuert das Zellwachstum, die Zellteilung und die Stoffwechselprozesse im Körper.






Medizinische Indikationen



Erkrankung Warum HGH eingesetzt? Typische Patienten


Wachstumsdepression bei Kindern Fördert Knochenlänge & Muskelmasse Kinder 18 Jahre mit diagnostiziertem Mangel


Prader-Willi-Syndrom Reduziert Fettmasse & erhöht Muskelkraft Patienten jeder Altersgruppe


Kronische Nierenerkrankung (CKD) Verbessert Kraft und Gewichtsaufbau CKD-Patienten, die keine ausreichende GH-Produktion haben


HIV-assoziierter Untergewicht Erhöht Muskelmasse & Energie HIV-Positive mit Gewichtsverlust



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Wirkmechanismen



Stimulation der Zellteilung – Wachstum von Knochen und Muskeln.


Metabolische Effekte – Förderung der Fettverbrennung, Reduktion des Blutzuckerspiegels.


Antioxidative Wirkung – Schutz vor oxidativem Stress.








Dosierung & Verabreichung



Alter Typische Dosis Verabreichungsweg


Kinder (6-12 Jahre) 0,05–0,1 µg/kg/Tag Subkutan, morgens


Jugendliche (13-18 Jahre) 0,1–0,15 µg/kg/Tag Subkutan, abends


Erwachsene 0,3–2,5 µg/kg/Tag Subkutan, einmal täglich





Anpassung: Basierend auf IGF-1-Werten und klinischer Reaktion.


Kombination: Oft mit Insulin oder Metformin bei Diabetes.








Vorteile



Vorteil Erläuterung


Verbessertes Körperbild Erhöhte Muskelmasse, reduzierte Fettanteile


Steigerte Knochendichte Reduziert Osteoporose-Risiko bei Erwachsenen


Erhöhte Energie Bessere körperliche Leistungsfähigkeit


Psychische Wirkung Verbesserte Stimmung und kognitive Funktion (bei AGHD)



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Häufige Nebenwirkungen



Nebenwirkung Häufigkeit Mögliche Gegenmaßnahmen


Ödeme, Schwellungen 10-20 % Reduktion der Dosis, Diuretika


Gelenk- & Muskelschmerzen 5-15 % Schmerzmittel, Ruhe


Hyperglykämie

Cheryl Voigt, 19 years

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